The relative rate technique was used to determine the rate constants of. It is a colorless liquid although commercial samples can appear yellowish. Polyvinylpyrrolidone vinylpyridine and vinypyrrolidone. Hydrogels of polyvinylpyrrolidone pvp and polyacrylic. Polyvinylpyrrolidone an overview sciencedirect topics. Polyvinyl pyrrolidone, find complete details about polyvinyl pyrrolidone,pvp,2 pyrrolidone,k30 polyvinyl pyrrolidone from pharmaceutical intermediates supplier or. Appearance white to light yellow, hygroscopic, amorphous powder density. Martindale the material may cause irritation or dermatitis in some individuals upon prolonged contact. Polyvinylpyrrolidone excipients for pharmaceuticals. Polyvinyl pyrrolidone was tested for carcinogenicity in mice, rats and rabbits by several routes of administration, producing local tumours. Nvinylpyrrolidone nvp is an organic compound consisting of a 5membered lactam linked to a vinyl group. Nmethylpyrrolidone, nmethyl 2pyrrolidinone, nmp c5h9no m 99, gmol. Us5538714a us08295,640 us29564094a us5538714a us 5538714 a us5538714 a us 5538714a us 29564094 a us29564094 a us 29564094a us 5538714 a us5538714 a us 5538714a authority us united states prior art keywords method composition polyvinyl pyrrolidone adherence anti prior art date 19920229 legal status the legal status is an assumption and is not a legal conclusion. Nylon 66 polyvinyl pyrrolidone reinforced composites.
Samples are desorbed with 955 methylene chloridemethanol and analyzed by gas chromatography with a flame ionization detector gcfid. It has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for. Synthesis and characterisation of poly vinylpyrrolidone. Nvinyl2pyrrolidone nvp is a chemical mainly used in the manufacture of ultraviolet screen printing inks and paper coatings. It is used as the precursor to polyvinylpyrrolidone. It can be used as monomer for polymerization, crosslinking monomers, and reactive diluents for uv curing. It is the precursor to polyvinylpyrrolidone pvp, an important synthetic material. The aim of this study was to gain some fundamental knowledge on the thermal degradation pathways of polynvinyl pyrrolidone using thermogravimetry coupled with fourier transform infrared spectroscopy tgftir in addition to ir and 1h nmr spectroscopic studies of the partially degraded samples. Cheng uei precision industry company has obtained a patent for a nanocomposite coating comprised of a nanometer inorganic oxide gel made by a solgel method and having 22. Nmethyl2pyrrolidone nmp is an organic compound consisting of a 5 membered lactam. The global chemicals industry faces economic and environmental pressures, thats why many of our suppliers like pyrrolidone factory are always innovating to provide more effective. It is produced industrially by vinylation of 2pyrrolidone, i. Adobe acrobat reader dc downloaden gratis pdfviewer voor.
Pvp was used as a plasma volume expander for trauma victims after the 1950s it is used as a binder in many pharmaceutical tablets. Novel biodegradable threedimensional 3d composites with good mechanical properties have been prepared by coagulation of a chitosan polyvinyl pyrrolidone cspvp solution in naoh. Bepaalde materialen, zoals lijsten, zoekresultaten, adviezen van comites, beslissingen van echa, informatiekaarten. Polyvinyl pyrrolidone is the linear polymer that consists of 1vinyl 2 pyrrolidone monomers conforming to the formula. Degradation properties required for the assessment as explained in the algorithm. Pierre braunstein, jacky rose, in comprehensive organometallic chemistry ii, 1995. Pvp has been shown to cause sarcomas in rats but there is not confirmation that it is carcinogenic in human patients. A wide variety of polyvinyl pyrrolidone options are available to you. The highest quality reference standards for reliable results. Poly1vinylpyrrolidonecostyrene 38 % emulsion in h 2 o, download fulltext pdf blends of polyvinyl pyrrolidone and polyacrylamide as corrosion inhibitors for aluminium in acidic medium article pdf available in indian journal of chemical technology 15. Polyvinylpyrrolidone is a typical tindependent type 2 antigen that is immunogenic in both enthymic and athymic nude mice andersson and blomgren, 1971.
Polyvinyl pyrrolidone deposits in the liver polyvinyl pyrrolidone iodine as an intravenous antiseptic adsorption behaviour of polyvinyl pyrrolidone on oxide surfaces. Switch to solventfree products or use mechanical methods. Samples are collected by drawing a known volume of air through a charcoal tube. Wo20107822a1 use of improved nalkyl pyrrolidone solvents. The primary aim of this study was to develop polyvinyl alcohol and polyvinyl pyrrolidone blended hydrogels and to evaluate their feasibility for delivering dh via a transdermal route. It has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems. Physicochemical properties, such as gel fraction %, swelling ratio. It was found that the vinyl pyrrolidone is the main volatile products of the. Polyvinylpyrrolidone definition of polyvinylpyrrolidone.
Complexation and blending of starch, polyacrylic acid. The mechanism for terminating the polymerization reaction makes it possible. Reactivity ratios of nvinylpyrrolidone acrylic acid. Copolymers of nvinylpyrrolidone nvp and acrylic acid aa were prepared by using hydrogen peroxide as initiator and water as solvent at 45.
Us5538714a use of polyvinyl pyrrolidone for reducing the. Pdf polyvinyl pyrrolidone pvp as an additive in starch. Fisher scientific one reagent lane fair lawn, nj 07410 for information in the us, call. Nvp is a slightly to moderately yellow heterocyclic, reactive vinyl monomer made from the reaction of acetylene and 2pyrrolidone. Nmethylpyrrolidone nmp harms the developing fetus when tested in pregnant animals. We use cookies to ensure that we give you the best experience of our website. This product in water, ethanol, insoluble in chloroform or ether.
Polyvinylpyrrolidone, also known as povidone or pvp, is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs. Nvinyl2pyrrolidone an overview sciencedirect topics. The effect of pvp on the morphology and electrochemical performance of binder free nicoldh electrode for supercapacitor were investigated in detail. Nvinyl2pyrrolidone nvp is either caustic stabilized with 0. Nickelcobalt layered double hydroxides nicoldh were successfully deposited on nickel foam by a facile hydrothermal method using polyvinyl pyrrolidone pvp as the structuredirecting reagent.
All quotes are valid for 30 days unless otherwise stated. This fact sheet is a summary of the priority existing chemical pec report at the time it was assessed and published. Protects high reactivity, exceptional quality and good consistency. The first polymerization product of nvinylpyrrolidone was soluble polyvinyl pyrrolidone, which was patented in 1939. The inherent properties of high polarity, low toxicity. Pvp polyvinylpyrolidone safety data sheet version 1.
Nvinyl2pyrrolidone cas 88120 watson international ltd. Transmission electron microscopy shows that welldispersed ultrafine alloy particles may be obtained. Download free adobe acrobat reader dc software for your windows, mac os and android devices to view, print, and comment on pdf documents. China pyrrolidone, pyrrolidone manufacturers, suppliers. Poly vinyl pyrrolidone is a water soluble polymer having a large number of consumer and environment friendly uses which are the consequences of its unique properties like biological compatibility, low toxicity, film. The copolymer reactivity ratio was computed by the fineman rose fr and kelen tudos kt method at lower conversion, using the. However, autopsies have found that crospovidone pvpp contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.
Cas number or watson number for noncas products 88120. For example, the strength and modulus of cspvp 11 were 82. Colloidal dispersions of bimetallic clusters are generally prepared by reduction of the metal halides in the presence of a protecting agent, for example, polynvinyl2pyrrolidone. The copolymers were characterized by ftir, h 1 nmr and c nmr. Nvinyl pyrrolidone nvp by basf is the best choice for a wide range of syntheses including polymerization, addition and electrocyclic reactions. Many wellknown reactions require waterfree conditions to initiate or complete the reaction. At the initial stage, the sample consists of a continuous, transparent and uniform phase of fully swollen gel grains with a slight excess of free water fig. Compatible with a wide range of hydrophilic and hydrophobic resins. Use of improved nalkyl pyrrolidone solvents download pdf. About 63% of these are pharmaceutical intermediates, 50% are syntheses material intermediates, and 31% are dyestuff intermediates. Inhalation of low concentrations of nvinyl2pyrrolidone by rats can cause nasal. Polyvinyl pyrrolidone, cyanomethyl diphenylcarbamodithioate average m n 6,000, pdi. Download fulltext pdf polyvinyl pyrrolidone pvp as an additive in starch based biodegradable films conference paper pdf available march 2014 with 514 reads.
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